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Heart block and hyperthyroidism. Report of two cases.

S Campus, A Rappelli, A Malavasi

    Archives of Internal Medicine
    |August 1, 1975
    PubMed
    Summary

    Hyperthyroidism can cause heart rhythm abnormalities, including heart block and P wave changes, even without pre-existing heart disease. These cardiac issues, seen in two patients, highlight the thyroid hormone

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    Area of Science:

    • Cardiology
    • Endocrinology
    • Internal Medicine

    Background:

    • Hyperthyroidism is associated with various cardiovascular complications.
    • Cardiac manifestations of hyperthyroidism can include arrhythmias and conduction abnormalities.
    • The relationship between hyperthyroidism and specific heart blocks requires further elucidation.

    Purpose of the Study:

    • To report on cardiac conduction abnormalities in patients with hyperthyroidism.
    • To describe the occurrence of first-degree heart block, P wave changes, and bundle-branch block in the context of hyperthyroidism.
    • To investigate the potential link between hyperthyroidism and transient complete heart block.

    Main Methods:

    • Case report of two patients with hyperthyroidism.
    • Clinical observation of cardiac rhythm and conduction.
    • Electrocardiographic (ECG) analysis including P wave morphology and heart block assessment.

    Main Results:

    • Two hyperthyroid patients without prior heart disease developed first-degree heart block with tall and large P waves.
    • One patient experienced left bundle-branch block and transient complete heart block with Stokes-Adams episodes.
    • No evidence of acute inflammatory disease was found in the affected patient.

    Conclusions:

    • Hyperthyroidism can manifest with significant cardiac conduction disturbances, including various types of heart block.
    • These findings suggest that thyroid hormone levels can directly impact cardiac electrical activity.
    • Further research is warranted to understand the mechanisms and clinical implications of these cardiac findings in hyperthyroidism.

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