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Chronic heart failure in the community: missed diagnosis and missed opportunities
K O Akosah1, K Moncher, A Schaper
1Gundersen Lutheran Medical Center, 1836 South Ave., La Crosse, WI 54601, USA.
Insights
Many patients admitted for shortness of breath with low ejection fraction have undiagnosed congestive heart failure (CHF). This missed diagnosis leads to high readmission rates and significant mortality, highlighting a critical gap in patient care.
Area of Science:
- Cardiology
- Internal Medicine
- Pulmonology
Background:
- Congestive heart failure (CHF) poses a significant burden due to its prevalence, cost, and impact on morbidity and mortality.
- Accurate incidence rates of CHF are challenging to ascertain due to reliance on discharge diagnoses and death certificates.
- Clinical judgment plays a crucial role in diagnosing CHF, yet diagnostic errors can occur.
Purpose of the Study:
- To determine the incidence of undiagnosed congestive heart failure (CHF) in hospitalized patients presenting with shortness of breath and low left ventricular ejection fraction (LVEF).
- To identify factors contributing to missed CHF diagnoses in this patient population.
- To assess the clinical outcomes, including readmission rates and mortality, associated with missed CHF diagnoses.
Main Methods:
- Retrospective review of 225 randomly selected patients admitted with shortness of breath and discharged without a CHF diagnosis (Group 1).
- Comparison of Group 1 with a control group (Group 2) of patients admitted with a confirmed CHF diagnosis, matched for age and LVEF.
- Diagnosis of CHF in Group 1 was based on the Framingham criteria.
Main Results:
- 51% of patients in Group 1 with low LVEF (< or =40%) met criteria for missed congestive heart failure (CHF).
- The readmission rate for patients with missed CHF was high at 42%, with 18% mortality at 12 months.
- While cardiomegaly was similar, third heart sound and heart rate > 120 beats/min were more frequent in the missed CHF group, whereas signs of fluid overload were more common in the diagnosed CHF group.
Conclusions:
- A substantial proportion of patients admitted with shortness of breath and low LVEF are not diagnosed with congestive heart failure (CHF).
- Physicians may overlook CHF diagnoses in patients without overt fluid overload, even with indicators like third heart sound and resting tachycardia.
- Missed CHF diagnoses are linked to high readmission rates and mortality comparable to newly diagnosed CHF patients.
Background:
The aim of this study was to determine the incidence of congestive heart failure (CHF) in patients discharged from a hospital without a diagnosis of CHF who were admitted with shortness of breath and had a low left ventricular ejection fraction (LVEF). CHF is a devastating disease in terms of financial cost, prevalence, and effect on morbidity and mortality. The true incidence rate is not known because of reliance on discharge records and death certificates, and because diagnosis remains a clinical judgment.
Methods And Results:
CHF was diagnosed by the Framingham criteria. We retrospectively reviewed the records of 225 randomly selected patients admitted with a complaint of shortness of breath and discharged without a diagnosis of CHF (group 1). We compared group 1 with patients admitted at the same time with a diagnosis of CHF and of similar age and LVEF (group 2). In group 1, 100 patients had a low LVEF (< or =40%) and 51% met criteria for CHF that had been missed. Readmission rate was high (42%). Mortality at 12 months was 18%. Rate of cardiomegaly on x-ray films was similar in groups 1 and 2 (64.6% v 64.4%, respectively). Third heart sound (39% v 10%; P <.001) and heart rate > 120 beats/min (41.7% v 12.5%; P <.001) were significantly more frequent in group 1. By contrast, signs and symptoms suggestive of fluid overload were more frequent in group 2.
Conclusions:
Many patients admitted with shortness of breath and low LVEF have CHF but are not diagnosed. Physicians are more likely to miss CHF in patients presenting without signs of fluid overload even when third heart sound is present with resting tachycardia. A missed diagnosis of CHF is associated with a high readmission rate, multiple admissions, and a mortality rate comparable to that of patients with newly diagnosed CHF.
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