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Omega-3 fatty acids decrease protein kinase expression in human breast cancer cells
N G Moore1, F Wang-Johanning, P L Chang
1Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294-3360, USA.
Breast Cancer Research and Treatment
|September 20, 2001
Abstract:
We report that 5-day exposure to physiological concentrations of eicosapentaenoic and docosahexaenoic acids resulted in a strong decrease in expression of the RIalpha regulatory subunit of protein kinase A and the PKC-alpha isozyme of protein kinase C in the human breast cancer cell line MDA-MB-231.