DNA-photocleavage agents
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Published on: April 20, 2017
T Da Ros1, G Spalluto, A S Boutorine
1Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Piazzale Europa 1, I-34127 Trieste, Italy. prato@univ.trieste.it
Current Pharmaceutical Design
|September 20, 2001
Abstract:
This review describes recent advances in the development of DNA-photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.
