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Modified cyclobutane carbonucleosides: synthesis and evaluation of their antiviral activity
F Fernández1, A R Hergueta, C López
1Dpto. Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15706 Santiago de Compostela, Spain.
Nucleosides, Nucleotides & Nucleic Acids
|September 21, 2001
Abstract:
The synthesis of some 9-(2-cyclobutylethyl)guanine derivatives and analogous carbonucleosides from 1S-alpha-pinene is here presented. None of them showed detectable selectivity when assayed in the performed anti-viral tests.