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A cyclobutane carbonucleoside with marked selectivity against TK+ and TK- varicella zoster virus
1Dpto. Química Orgánica, Universidade de Santiago, E-15706, Santiago de Compostela, Spain.
Nucleosides, Nucleotides & Nucleic Acids
|September 21, 2001
Abstract:
Several cyclobutyladenine and analogous carbonucleosides were synthesized from 1R-alpha-pinene and their anti-viral activity was tested. One of them (3e) showed interesting selectivity against both TK+ and TK- VZV.