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6-azacytidine--compound with wide spectrum of antiviral activity
I Alexeeva1, N Dyachenko, L Nosach
1Institute of Molecular Biology and Genetics, Kyiv, Ukraine.
Nucleosides, Nucleotides & Nucleic Acids
|September 21, 2001
Abstract:
6-azacytidine demonstrates activity against adenoviruses types 1, 2, 5. It inhibit synthesis of viral DNA and proteins. 6-AC shows antiherpetic and antiinfluenza action during experimental infection in mice. 6-AC is prospective for drug development as an antiviral substance with a wide spectrum of activity.