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Bridged cyclic oligoribonucleotides--towards models for codon-anticodon pairing
1Institute of Chemistry, University of Linz, Altenbergerstr. 69, A-4040 Linz, Austria.
Nucleosides, Nucleotides & Nucleic Acids
|September 21, 2001
Abstract:
Only three base pairs make up for stable double helices of regular A-type if both helix ends are bridged by flexible non-nucleotide linkers. These cyclic oligoribonucleotides are used as model systems for codon-anticodon pairing in order to reveal base stacking effects arising from structurally relevant bases in the direct neighbourhood of the core triplet duplex.