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Four color fret dye nucleotide terminators for DNA sequencing
T S Rao1, S Nampalli, K Lavrenov
1Amersham Pharmacia Biotech., 800 Centennial Avenue, Piscataway, New Jersey 08855, USA.
Nucleosides, Nucleotides & Nucleic Acids
|September 21, 2001
Abstract:
The synthesis of four color set of energy transfer-dye terminators (8a-8d) starting from p-iodo-beta-phenylalanine was accomplished and their utility in the sequencing reactions has been evaluated.