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Related Experiment Videos

Kawasaki disease--Indian perspective.

R N Pendse1, H Bhandari, A K Vats

  • 1Bhandari Children Hospital, 90-L-Road, Bhupalpura, Udaipur, Rajasthan, India.

Indian Journal of Pediatrics
|September 21, 2001
PubMed
Summary

Kawasaki disease, a rare condition in India, typically affects young children. Indian patients exhibit a lower incidence of cardiac complications compared to Western populations, suggesting a milder disease course.

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Area of Science:

  • Pediatrics
  • Cardiology
  • Rheumatology

Background:

  • Kawasaki disease is an acute febrile illness of unknown cause, primarily affecting children under five.
  • It is a significant cause of acquired heart disease in developed nations.
  • The incidence and reported cases of Kawasaki disease in India are notably low.

Observation:

  • This report details two pediatric cases of Kawasaki disease in India, both presenting with a benign clinical course.
  • A comparative analysis with Western literature was performed.
  • Cardiac complication rates were specifically examined in Indian versus Western patients.

Findings:

  • Indian patients with Kawasaki disease showed a cardiac complication rate of approximately 10%.
  • This contrasts with Western literature, where cardiac complication rates are reported around 30%.
  • The observed lower incidence of cardiac issues in Indian children may explain the infrequent reporting of this condition in India.

Implications:

  • The findings suggest a potentially milder presentation or lower predisposition to cardiac sequelae in Indian children with Kawasaki disease.
  • This could influence diagnostic and management strategies in regions with low reported incidence.
  • Further research is warranted to understand the epidemiological and etiological factors contributing to these geographical differences.

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