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Clostridium difficile small bowel enteritis occurring after total colectomy.

J F Freiler1, S J Durning, P T Ender

  • 1Department of Internal Medicine, Wright-Patterson Medical Center, Wright-Patterson Air Force Base, OH 45433-5529, USA. jdfreiler@earthlink.net

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|September 21, 2001
PubMed
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Clostridium difficile infection typically affects the colon. This report details a rare case of small bowel enteritis caused by C. difficile post-colectomy, reviewing similar cases.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Microbiology

Background:

  • Clostridium difficile infection (CDI) is a significant cause of antibiotic-associated diarrhea.
  • CDI is predominantly confined to the colonic mucosa.
  • Small bowel involvement in CDI is exceptionally rare.

Observation:

  • This report presents a unique case of C. difficile enteritis in a patient following a total colectomy.
  • The patient developed symptoms indicative of small bowel inflammation.

Findings:

  • Review of the literature identified only 9 previously reported cases of C. difficile enteritis.
  • This case adds to the scarce evidence of CDI affecting the small intestine, particularly in the post-colectomy setting.

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Implications:

  • Highlights the potential for C. difficile to cause enteritis beyond the colon, especially in altered gastrointestinal anatomy.
  • Suggests the need for considering CDI in the differential diagnosis of small bowel inflammation in specific patient populations.
  • Underscores the importance of understanding the diverse clinical manifestations of C. difficile infection.