Related Experiment Video
Updated: Sep 21, 2026

Determination of the Gas-phase Acidities of Oligopeptides
Published on: June 24, 2013
[Specific features of night acidity in patients with peptic duodenal ulcers and primary chronic gastroduodenitis]
Abstract:
The peculiarities of nightly acid formation in the patients with peptic ulcer (PU) and primary chronic gastroduodenitis (PCG) were examined with apparatus "Gastroskan-24", that has computer's program to evaluate the data of intragastric 24-hours pH measurement. 24 patients with PU and 36 patients with PCG were examined. The increase of nightly acid formation was higher in the patients with PU versus the patients with PCG. It was revealed that pH depends on smoking. The possibility of risk group to peptic ulcer definition was demonstrated in patients with PCG.
Related Concept Videos
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds to M3...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease I: Introduction
Peptic Ulcer Disease III: Clinical Manifestations and Complications

