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Published on: March 11, 2014
Inverted papilloma: a review of 53 cases.
M A Thorp1, M F Oyarzabal-Amigo, J H du Plessis
1Department of Otolaryngology, University of Cape Town, Groote Schuur Hospital, Observatory, South Africa.
The Laryngoscope
|September 25, 2001
Summary
Aggressive surgical management of inverted nasal papilloma is crucial, as this study of 53 patients showed a 28% recurrence rate and 9% malignant association. Early, extensive treatment is recommended.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Oncology
Background:
- Inverted papilloma is a benign sinonasal tumor with a high recurrence rate and potential for malignant transformation.
- Surgical management strategies vary, impacting patient outcomes.
Purpose of the Study:
- To evaluate the surgical management and outcomes of inverted nasal papilloma over a 14-year period.
- To determine recurrence rates and the incidence of malignant association.
Main Methods:
- Retrospective study design.
- Analysis of 53 patients treated at a tertiary health care center.
- Review of surgical interventions and long-term follow-up data.
Main Results:
- A total of 53 patients (38 males, 15 females; average age 49.8 years) were included.
- Overall recurrence rate was 28%, with a 9% rate of malignant association.
- Recurrence rates were similar for extensive disease (27%) and less extensive disease (30%) treated conservatively.
- Malignant transformation occurred in 6% of all patients.
Conclusions:
- Aggressive initial surgical management is the recommended therapeutic approach for inverted nasal papilloma.
- Early and comprehensive treatment may reduce recurrence and the risk of malignancy.
