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Updated: Jul 27, 2026
RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Inverted papilloma: a review of 53 cases
M A Thorp1, M F Oyarzabal-Amigo, J H du Plessis
1Department of Otolaryngology, University of Cape Town, Groote Schuur Hospital, Observatory, South Africa.
Objective:
To assess the surgical management of patients with inverted nasal papilloma over a 14-year period.
Study Design:
Retrospective study.
Setting:
Tertiary health care center.
Results:
Fifty-three patients (38 males, 15 females) with an average age of 49.8 years were treated. Overall recurrence rate was 28% and a malignant association of 9% was shown. Recurrence rates varied from 27% in patients with more extensive disease involvement treated by lateral rhinotomy and medial maxillectomy, to 30% in patients with less extensive disease treated conservatively. Of the 5 patients with associated malignancy, 3 (6% of all patients) are likely to have undergone malignant transformation.
Conclusion:
Aggressive initial management remains the therapeutic aim in this condition.
