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One or two hours postprandial glucose measurements: are they the same?
1Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, and Sackler School of Medicine, Tel-Aviv University, Israel.
American Journal of Obstetrics and Gynecology
|September 25, 2001
Summary
This study found that abnormal glucose levels in gestational diabetes mellitus (GDM) occur more frequently 1 hour after breakfast and 2 hours after dinner. Differential blood glucose monitoring may improve GDM management.
Area of Science:
- Endocrinology
- Obstetrics
- Metabolic Disorders
Background:
- Gestational diabetes mellitus (GDM) affects pregnant women, requiring careful blood glucose monitoring.
- Standard postprandial glucose monitoring protocols may not capture all instances of hyperglycemia.
Purpose of the Study:
- To compare the incidence of abnormal glucose levels 1 hour versus 2 hours postprandially in women diagnosed with GDM.
- To evaluate the efficacy of differential postprandial glucose measurement timing for GDM management.
Main Methods:
- Sixty-eight women with GDM (Carpenter-Coustan criteria) were studied.
- Daily fasting, 1-hour, and 2-hour postprandial glucose levels were self-monitored for one week.
- Women with fasting glucose ≥105 mg% were excluded; all initially managed with diet.
Main Results:
- Postbreakfast: 22.4% abnormal levels at 1 hour vs. 8.5% at 2 hours (P < .01).
- Postdinner: 16.3% abnormal levels at 1 hour vs. 30.1% at 2 hours (P < .01).
- Postlunch showed no significant difference between 1-hour and 2-hour measurements.
Conclusions:
- The timing of postprandial glucose measurement significantly impacts the detection of hyperglycemia in GDM.
- Measuring glucose 1 hour after breakfast and 2 hours after dinner may provide stricter glycemic control criteria.
- Further research is warranted to determine if differential monitoring reduces GDM-associated complications.