Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vancomycin prophylaxis in joint arthroplasty.

A Savarese1, M L Nanni, C Pasquali

  • 1Divisione di Ortopedia e Traumatologia, Ospedale, Manerbio.

La Chirurgia Degli Organi Di Movimento
|September 25, 2001
PubMed
Summary

Postoperative infections are a significant challenge in prosthetic surgery. Perioperative antibiotic prophylaxis, specifically vancomycin, can reduce infection risk in hip and knee arthroplasty procedures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of the molecular tumor board: learnings from the ROME trial.

NPJ precision oncology·2026
Same author

ENGOT-en11/GOG-3053/KEYNOTE-B21: a randomised, double-blind, phase III study of pembrolizumab or placebo plus adjuvant chemotherapy with or without radiotherapy in patients with newly diagnosed, high-risk endometrial cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Risk of preoperative understaging of duodenal neuroendocrine neoplasms: a plea for caution in the treatment strategy.

Journal of endocrinological investigation·2021
Same author

Carboplatin-paclitaxel compared to Carboplatin-Paclitaxel-Bevacizumab in advanced or recurrent endometrial cancer: MITO END-2 - A randomized phase II trial.

Gynecologic oncology·2019
Same author

Conservative surgery in stage I adult type granulosa cells tumors of the ovary: Results from the MITO-9 study.

Gynecologic oncology·2019
Same author

Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.

International journal of cancer·2019

Area of Science:

  • Orthopedic Surgery
  • Infectious Disease
  • Pharmacology

Background:

  • Postoperative infections in prosthetic surgery are difficult to treat due to antibiotic-resistant microbial agglomerates.
  • Prosthesis removal is often the only solution for established infections.
  • Antibiotic prophylaxis can decrease infection risk in such surgeries.

Purpose of the Study:

  • To evaluate perioperative antibiotic prophylaxis strategies in hip and knee arthroplasty.
  • To present a case series on the use of vancomycin for infection prevention.

Main Methods:

  • A case series of 233 joint arthroplasties performed between October 1993 and April 1996.
  • Perioperative prophylaxis with vancomycin chlorohydrate (1g IV) administered 1 hour pre-surgery and 6-8 hours post-surgery.

Main Results:

  • Vancomycin prophylaxis was administered in all cases.
  • The antibiotic choice was guided by epidemiological data and clinical experience.

Conclusions:

  • Systematic perioperative antibiotic prophylaxis is advantageous in reducing infection risk.
  • Vancomycin is a potential agent for prophylaxis in hip and knee arthroplasty.
  • Further research may explore optimal antibiotic strategies for prosthetic joint infections.

Related Experiment Videos