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Persistent pulmonary hypertension of the newborn. Rational therapy based on pathophysiology
1Department of Pediatrics, Case Western Reserve University, Neonatal Intensive Care Unit, Cleveland, Ohio, USA.
Clinics in Perinatology
|September 26, 2001
Abstract:
Persistent pulmonary hypertension of the newborn is a common disorder among near-term gestation newborns. Persistent pulmonary hypertension of the newborn is characterized by hypoxemia that is frequently refractory to conventional management. This article describes the pathophysiologic basis of the disorder and the current therapy that is based on this knowledge.