Echovirus type 13--United States, 2001

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    MMWR. Morbidity and Mortality Weekly Report
    |September 26, 2001
    PubMed

    Insights

    Echovirus 13, a rare enterovirus, is increasingly detected in the US, primarily causing aseptic meningitis. Public health officials are investigating outbreaks, urging consideration of Echovirus 13 in differential diagnoses.

    Area of Science:

    • Virology
    • Public Health
    • Infectious Diseases

    Background:

    • Echoviruses are a major group of enteroviruses linked to various illnesses.
    • Echovirus 13 is historically rare in the US, with few reported isolates between 1970-2000.
    • No Echovirus 13 outbreaks were previously reported in the United States.

    Purpose of the Study:

    • To summarize Echovirus 13 activity in the United States.
    • To highlight the investigation of aseptic meningitis outbreaks linked to Echovirus 13.
    • To inform clinicians about Echovirus 13 as a potential cause of aseptic meningitis.

    Main Methods:

    • Surveillance data from CDC on enterovirus isolates.
    • Reports from state and private public health laboratories.
    • Investigation of aseptic meningitis outbreaks in multiple US states.

    Main Results:

    • An increase in Echovirus 13 isolates reported to CDC as of June 2001.
    • Most identified Echovirus 13 isolates were associated with aseptic meningitis.
    • Outbreaks investigated in Louisiana, Mississippi, Montana, and Tennessee.

    Conclusions:

    • Echovirus 13 activity has increased in the United States.
    • Aseptic meningitis is a key clinical manifestation of Echovirus 13 infection.
    • Echovirus 13 should be considered in the differential diagnosis of aseptic meningitis.

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