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Satellite potentials on EMG: neurophysiologic evidence of axonal transection in MS?
G Antonini1, S Morino, F Giubilei
1Department of Neurological Sciences, University of Rome, La Sapienza, Italy. antoninimusc@uniroma.it
Neurology
|September 26, 2001
Abstract:
To detect signs of axonal damage in MS, the authors investigated the occurrence in EMG of motor unit action potentials with satellite potentials (SP-MUAP) in the upper limb muscles in 10 consecutive patients with MS with cervical spinal cord demyelinating lesions and 10 control subjects. Subjects' SP-MUAP rate was 0 to 2.5% (median 0%) in the control group, and 0 to 17.5% (median 7.5%) in the MS group (p < 0.01). Motor unit remodeling secondary to axonal transection of spinal motor neurons traversing cervical demyelinating lesions may be hypothesized.