Adrenal incidentaloma
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Updated: Oct 4, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
1Department of Surgery, Section of Endocrine and Oncologic Surgery, Washington University School of Medicine, 6605 Euclid Ave., Campus Box 8109, St. Louis, Missouri 63110, USA.
Abstract:
Because of the frequent use of computed tomography and other abdominal imaging modalities, clinicians more frequently see the incidentally discovered, clinically silent adrenal mass. Most adrenal incidentalomas should be evaluated for hormonal activity and assessed for their risk of malignancy. Adrenalectomy is indicated for hyperfunctioning tumors and for any potential primary malignant adrenal lesion. Nonfunctioning cortical adenomas < 4 to 5 cm in size should be followed clinically and radiographically. Laparoscopic adrenalectomy has been used increasingly as the preferred approach in patients who require surgical resection whereas open adrenalectomy is reserved for patients with large, malignant tumors. The indications for adrenalectomy in patients with nonfunctioning adrenal tumors should not be liberalized because of the laparoscopic approach.
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