Related Experiment Video
Updated: Oct 4, 2026

Establishment of Zone-Enriched Primary Cultures from the Mouse Adrenal Cortex
Published on: May 8, 2026
Genetic background of adrenocortical tumor development
M Kjellman1, C Larsson, M Bäckdahl
1Department of Surgery, P9:03, Karolinska Hospital, S-17176, Stockholm, Sweden. kmak@kir.ks.sc
Abstract:
The increasing occurrence of incidentally discovered benign adrenocortical tumors has become a clinical dilemma because of the difficulties in differentiating them from their malignant counterpart. Adrenocortical tumors are associated with familial cancer syndromes such as the Beckwith-Wiedemann syndrome, the Li-Fraumeni syndrome, the Carney complex, multiple endocrine neoplasia type 1, congenital adrenal hyperplasia, and the McCune-Albright syndrome. Genetic events are known to take place on the chromosomal and gene level in sporadic adrenocortical tumors.
Related Concept Videos
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Cushing Syndrome I: Introduction
Cushing Syndrome II: Pathophysiology
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Cancers Originate from Somatic Mutations in a Single Cell
Cancer Prevention
Some...
