Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Polygraphy of a panic attack].

H U Noffke1, M Roser

  • 1Bürgerhospital, Klinik für Psychiatrie und Psychotherapie, Tunzhofer Str. 14-16, 70191 Stuttgart.

Der Nervenarzt
|September 27, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Informations on psychotropics and their adaptations for patients suffering from mental disorders in France during the SARS-CoV-2 epidemic].

L'Encephale·2020
Same author

Incidence of MRI-detected brain lesions and neurocognitive function after electrical cardioversion in anticoagulated patients with persistent atrial fibrillation.

International journal of cardiology·2017
Same author

[Right ventricular outflow tract tachycardia 30 years after surgical correction of tetralogy of Fallot].

Herzschrittmachertherapie & Elektrophysiologie·2015
Same author

[Cardiac resynchronisation with atrial sensing: Is it feasible?].

Herzschrittmachertherapie & Elektrophysiologie·2015
Same author

Polyploidy and hybridization as main factors of speciation: complex reticulate evolution within the grass genus Helictochloa.

Cytogenetic and genome research·2014
Same author

[New applications in maxillofacial surgery: Local injections with botulinum toxin type A].

Mund-, Kiefer- und Gesichtschirurgie : MKG·2013
Same journal

[Psychotropic drug research in Germany: challenges of early benefit assessment and precision psychiatry].

Der Nervenarzt·2026
Same journal

[When brain abscesses run in the family…].

Der Nervenarzt·2026
Same journal

[Digital health applications and adherence in depression: a qualitative study from the perspective of healthcare providers].

Der Nervenarzt·2026
Same journal

Der Nervenarzt·2026
Same journal

[Rare genetic diseases with frequent mental symptoms].

Der Nervenarzt·2026
Same journal

Der Nervenarzt·2026
See all related articles

This study recorded a spontaneous panic attack in a patient with Type 1 diabetes and depression. Findings reveal distinct physiological phases and a paradoxical heart-respiratory response preceding anxiety.

Area of Science:

  • Psychiatry
  • Neuroscience
  • Cardiology

Background:

  • This study investigated the physiological correlates of panic attacks in a patient with Type 1 diabetes mellitus and a major depressive episode with panic disorder.
  • The patient experienced a spontaneous panic attack while at rest, which was serendipitously recorded using polysomnography.

Observation:

  • Physiological parameters including electrocardiogram, finger blood flow, respiratory rhythm, and muscle tone were monitored.
  • A triphasic panic attack pattern was observed, comprising an initial phase (140s), a dynamic phase (80s), and a declining phase (180s).
  • The dynamic phase was marked by acute fingertip vasoconstriction and increased heart rate, with the patient unaware of the attack's onset.

Findings:

  • Central regulation confirmed sympathetic-norepinephrine activation at panic attack onset, without musculoskeletal system activation.

Related Experiment Videos

  • A paradoxical heart rate increase and simultaneous respiratory rate decline preceded anxiety, suggesting non-antagonistic ergotropic-trophotropic system regulation.
  • The patient's autonomic state indicated homeostatic lability, potentially predisposing to panic attacks as a central nervous system response.

    • Implications:

    • This case highlights the complex interplay between diabetes, depression, and panic disorder.
    • Understanding the autonomic nervous system's role in panic attacks can inform novel therapeutic strategies.
    • The findings suggest that panic attacks may represent a CNS response to homeostatic dysregulation.