AKT plays a central role in tumorigenesis

BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.

Leukemia·2012

Beta-catenin inhibits melanocyte migration but induces melanoma metastasis.

Oncogene·2012

Transcription Factor DLX5 As a New Target for Promising Antitumor Agents.

Acta naturae·2012

The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival.

Oncogene·2009

Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study.

Multiple sclerosis (Houndmills, Basingstoke, England)·2008

Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition.

Oncogene·2007

The effectiveness of green place-based industrial policy: Evidence from the Inflation Reduction Act.

Proceedings of the National Academy of Sciences of the United States of America·2026

Overcoming the blood-brain barrier using central nervous system-accessing lipid nanoparticles for enhanced mRNA therapeutics.

Proceedings of the National Academy of Sciences of the United States of America·2026

Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition.

Proceedings of the National Academy of Sciences of the United States of America·2026

Emergence of biosignatures on Earth and implications for life detection.

Proceedings of the National Academy of Sciences of the United States of America·2026

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10.

Proceedings of the National Academy of Sciences of the United States of America·2026

Beyond "non-significant" results: Why and how to test for practical equivalence.

Proceedings of the National Academy of Sciences of the United States of America·2026

DLL3 serves as a pivotal hub bridging malignant progression and immunosuppression in NECC with therapeutic implications validated via the organoid-TIL co-culture system.

Genes & diseases·2026

Candida Albicans Purulent Pericarditis Complicated by Cardiac Tamponade in a Critically Ill Burn Patient: A Case Report.

Journal of the Saudi Heart Association·2026

Advances in quinazolin-4-one scaffolds in breast cancer therapy: emerging designs, mechanistic perspectives and SAR trends (2015-2025).

RSC medicinal chemistry·2026

Decoding the role of exosomes in bladder cancer: focusing on tumor progression and immune microenvironment modulation.

Frontiers in oncology·2026

BUB1 regulates cell proliferation and apoptosis in cervical cancer by AKT signaling and autophagosome-lysosome fusion via ACTN1.

iScience·2026

Human relevant platforms for cutaneous wound healing research: current landscape, translational gaps, and emerging frontiers.

Frontiers in bioengineering and biotechnology·2026

Related Experiment Videos

AKT plays a central role in tumorigenesis

Related Concept Videos

BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.

Beta-catenin inhibits melanocyte migration but induces melanoma metastasis.

Transcription Factor DLX5 As a New Target for Promising Antitumor Agents.

The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival.

Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study.

Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition.

The effectiveness of green place-based industrial policy: Evidence from the Inflation Reduction Act.

Overcoming the blood-brain barrier using central nervous system-accessing lipid nanoparticles for enhanced mRNA therapeutics.

Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition.

Emergence of biosignatures on Earth and implications for life detection.

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10.

Beyond "non-significant" results: Why and how to test for practical equivalence.

DLL3 serves as a pivotal hub bridging malignant progression and immunosuppression in NECC with therapeutic implications validated via the organoid-TIL co-culture system.

Candida Albicans Purulent Pericarditis Complicated by Cardiac Tamponade in a Critically Ill Burn Patient: A Case Report.

Advances in quinazolin-4-one scaffolds in breast cancer therapy: emerging designs, mechanistic perspectives and SAR trends (2015-2025).

Decoding the role of exosomes in bladder cancer: focusing on tumor progression and immune microenvironment modulation.

BUB1 regulates cell proliferation and apoptosis in cervical cancer by AKT signaling and autophagosome-lysosome fusion via ACTN1.

Human relevant platforms for cutaneous wound healing research: current landscape, translational gaps, and emerging frontiers.

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AKT plays a central role in tumorigenesis

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