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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

A completely foreign receptor can mediate an interferon-gamma-like response

B Strobl1, V Arulampalam, H Is'harc

  • 1Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

The EMBO Journal
|September 28, 2001
PubMed
Summary

Constructing chimeric receptors reveals insights into JAK/STAT signaling pathways. Minor modifications to receptor complexes significantly impact cellular responses, highlighting modularity in signal transduction.

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