Related Experiment Video
Updated: Aug 15, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
Echocardiographic assessment of diastolic function
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA. ommen.steve@mayo.edu
Insights
Abnormal diastolic function significantly impacts heart health. Echocardiography, using Doppler variables, is vital for assessing and understanding this condition for better patient outcomes.
Area of Science:
- Cardiology
- Cardiac Physiology
Background:
- Abnormal diastolic function is a significant factor in cardiac morbidity and mortality.
- Accurate noninvasive assessment is essential for understanding and managing diastolic impairment.
Purpose of the Study:
- To review recent echocardiographic advancements in assessing diastolic function.
- To highlight the clinical impact of echocardiography in the field of diastology.
Main Methods:
- Review of current echocardiographic parameters for diastolic function assessment.
- Focus on both established and novel Doppler echocardiographic variables.
Main Results:
- Echocardiography is the primary noninvasive tool for evaluating diastolic function.
- Ongoing research into Doppler variables aims for more standardized assessment.
Conclusions:
- Echocardiographic assessment is crucial for understanding diastolic dysfunction.
- Advancements in echocardiography are key to addressing future challenges in cardiac pathophysiology.
Abstract:
Abnormal diastolic function is increasingly appreciated as a major contributor to cardiac morbidity and mortality. Accurate noninvasive assessment of the presence and severity of diastolic impairment is crucial to the broad application and understanding of this common condition. Echocardiographic parameters have become the backbone of this noninvasive assessment. Active investigation into both old and new Doppler variables will provide the framework that can lead to a more uniform assessment and reporting that will be essential as we prepare to confront clinically the next frontier in cardiac pathophysiology. This review discusses the clinical impact of recent echocardiographic contributions to the field of diastology.
Related Concept Videos
Assessment of the Cardiovascular System IV: Auscultation
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...

