[Effect of calcium ion level in blood on physiological functions in rat subjected to immersion hypothermia]
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Updated: Oct 4, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
1I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
Abstract:
I.v. administration of disodium salt of the ethylenediamine tetra-acetic acid to continuously immersed white rats intensified the rats' amplitude and rate of the respiration movement. I.v. administration of calcium chloride to the cooled rats diminished by 11.3% the respiration movement amplitude and by 20.7%--the muscles electrical activity. The findings confirm important role of the calcium ions in infringement of physiological functions under conditions of hypothermia.
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