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Updated: Jul 27, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Optic neuritis: a novel presentation of Schilder's disease
A K Afifi1, K A Follett, J Greenlee
1Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City 52242, USA. adel_afifi@uiowa.edu
Abstract:
The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease.
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