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Published on: November 29, 2010
Amelanotic malignant melanoma arising in an ovarian cystic teratoma: a case report
Y Watanabe1, H Ueda, H Nakajima
1Department of Obstetrics and Gynecology, Kinki University School of Medicine, Osaka, Japan. watanabe@med.kindai.ac.jp
Background:
Malignant melanoma arising in a cystic teratoma is extremely rare. We report the clinicopathologic and cytopathologic features of an amelanotic malignant melanoma arising in an ovarian cystic teratoma.
Case:
A 55-year-old woman presented with an asymptomatic right ovarian mass, showing features of cystic teratoma according to preoperative computed tomography and magnetic resonance imaging. The resected teratoma was suspected to include a nonepithelial malignancy in a touch preparation from a solid component. The tumor showed immunoreactivity for Melan-A, S-100 and HMB-45 in the absence of melanin granules, which established the diagnosis of amelanotic malignant melanoma arising in an ovarian cystic teratoma.
Conclusion:
Cytopathologic findings from touch preparations and immunohistochemical staining are useful for the diagnosis of amelanotic malignant melanoma arising in an ovarian cystic teratoma.
