Snakebite complicated with Vibrio vulnificus infection.

Area of Science:

• Infectious Diseases
• Toxicology
• Wound Healing

Background:

• Snakebites can lead to bacterial infections, predominantly Gram-negative bacilli.
• Vibrio vulnificus infections present with necrotizing wound infections, mimicking severe snakebite local effects.
• This is the first reported case of snakebite complicated by Vibrio vulnificus.

Purpose of the Study:

• To report a novel case of snakebite complicated by Vibrio vulnificus infection.
• To highlight the clinical presentation and management of this rare complication.
• To emphasize the importance of considering severe bacterial infections in refractory snakebite cases.

Main Methods:

• Case report of a 79-year-old male with snakebite.
• Clinical assessment including rapid progression of hemorrhagic bulla, necrotizing fasciitis, compartment syndrome, and septic shock.
• Microbiological culture of necrotic tissue, identifying Vibrio vulnificus.
• Surgical debridement and fasciotomy.
• Antibiotic treatment and reconstructive surgery.

Main Results:

• The patient developed severe local and systemic complications following snakebite.
• Vibrio vulnificus was successfully cultured from necrotic tissue.
• Aggressive debridement, fasciotomy, and antibiotic therapy led to patient recovery.
• Multiple reconstructive surgeries were required.

Conclusions:

• Severe bacterial infections, including Vibrio vulnificus, should be considered in snakebite patients unresponsive to standard antivenom therapy.
• Prompt and aggressive medical and surgical intervention is critical for managing such severe infections.
• This case expands the spectrum of potential complications following snakebite.