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Prediction of malignancy using transvaginal color flow Doppler in patients with gynecologic tumors
J.R. Carter1, J.M. Fowler, J.W. Carlson
1Women's Cancer Center, Department of Obstetrics and Gynecology, University of Minnesota, Box 395 Mayo Memorial Building, Minneapolis, MN 55455, USA.
Abstract:
Eighty-five patients referred to the Women's Cancer Center, University of Minnesota had transvaginal color flow Doppler performed to determine if pelvic malignancy could be predicted by blood flow assessment. Their mean age was 49 years (range 21-86 years). Thirty-five patients were subsequently found to have malignant tumors of the cervix, uterus or ovary. The presence of increased intratumoral blood flow as depicted by color flow Doppler had a sensitivity of 83%, specificity of 100%, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 89% for malignancy. The mean intratumoral Pulsatility Index (PI) of the patients with malignant tumors was 0.81 (SD 0.24; range 0.3-1.2), which was significantly lower than for the benign group (P = 0.001). A PI of