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Updated: Oct 4, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Extraperitoneal metastases after intraperitoneal chemotherapy of ovarian cancer patients with a negative second-look
J. Menczer1, G. Ben-Baruch, S. Rizel
1Department of Obstetrics and Gynecology and Oncology, The Chaim Sheba Medical Center, Tel Hashomer, Affiliated to the Sackler School of Medicine, Tel Aviv University, Israel.
Abstract:
The site of the first detectable recurrence was recorded in 17 consecutive stage II-IV ovarian carcinoma patients who, after a negative second-look laparotomy, received intraperitoneal chemotherapy with cisplatin and thiosulfate kidney protection. Although the progression-free interval and survival were favorable, 11 patients eventually had a recurrence and in six (54.5%) of these it was extraperitoneal. Brain metastases were detected in three patients. The appearance of extraperitoneal metastases is not always ominous.
