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The LonStenn-a new cervical sampling device.

H.M. Stenning1, D.B.B. Stenning, G.R. Rajasekariah

  • 1Save the Cervix (International), PO Box 305, Mosman, NSW 2088General Clinical Laboratories, 6 Holt St., North Sydney, NSW 2060University of Sydney, NHMRC Clinical Trial Centre, Parramatta Rd, Camperdown, NSW 2051, Australia.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
|November 1, 1995
PubMed
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The new LonStenn cervical sampling device effectively collects more cells for Pap smears compared to traditional methods. This improved cell collection may reduce false negatives in laboratory diagnoses.

Area of Science:

  • Gynecologic Oncology
  • Cervical Cytology
  • Medical Device Evaluation

Background:

  • Cervical cancer screening relies on Papanicolaou (Pap) smears for early detection.
  • Effective cell collection is crucial for accurate cytological analysis.
  • Existing cervical sampling devices have limitations in cell yield and transfer.

Purpose of the Study:

  • To evaluate the performance of a novel cervical sampling device, the 'LonStenn'.
  • To compare the LonStenn's cell collection efficiency against the Cervex Brush and CytoBrush/Ayres Spatula.
  • To assess the impact of sampling method on cell transfer to glass slides for cytological evaluation.

Main Methods:

  • A comparative study involving 180 patients undergoing Pap smears.
  • Three sampling devices were used: LonStenn, Cervex Brush, and CytoBrush/Ayres Spatula.

Related Experiment Videos

  • Cell counts were performed on residual cells left on the device and cells transferred to slides, using a Kova Slide Chamber.

    • Main Results:

    • The LonStenn device demonstrated superior quantitative delivery of harvested cervical cells to glass slides.
    • Qualitative assessment indicated improved smear quality with less blood staining when using the LonStenn.
    • The study quantified cell entrapment, a potential cause of false negatives, for each device.

    Conclusions:

    • The LonStenn cervical sampling device is more efficient in collecting and delivering representative cells for cytological analysis.
    • Improved cell transfer and reduced artifact (e.g., blood staining) suggest potential for decreased false-negative rates.
    • The LonStenn represents a promising advancement in cervical cytology sampling technology.