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Updated: Aug 12, 2026

Generation of Human Monocyte-derived Dendritic Cells from Whole Blood
Published on: December 24, 2016
Dendritic cells: their significance in health and disease
1Department of Pathology, Institute of Experimental Immunology, University of Zurich, CH-8091, Zurich, Switzerland.
Abstract:
Dendritic cells (DCs) represent a heterogeneous population of professional antigen-presenting cells. Precursor cells move via the blood to peripheral tissues. These immature DCs can take up invading pathogens and then rapidly migrate to the draining secondary lymphoid organs. Converted into antigen-presenting mature DCs, these cells are able to prime naive T cells and to initiate an adoptive immune response. The extraordinary functional profile suggests that, under certain preconditions, DCs may represent an ideal vector in the immunotherapy of cancer and infectious diseases
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