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Updated: Oct 4, 2026

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
Published on: June 14, 2016
Polymorphism of the human muc genes
J Fowler1, L Vinall, D Swallow
1Galton Laboratory, Department of Biology, Wolfson House, 4 Stephenson Way, London NW1 2HE.
Abstract:
Mucins encoded by the MUC genes share the common feature of having an extensive tandem repeat region that encompasses a large proportion of the coding sequence. In many of the genes this tandem repeat region shows a great deal of allelic length variation and recently studies have demonstrated person to person variation in pattern of nucleotide or amino-acid changes in the repeat units. The length and sequence variability will be discussed in this review, as will its role in disease susceptibility.
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