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The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
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Separating attention deficit hyperactivity disorder and learning disabilities in girls: a familial risk analysis.

A E Doyle1, S V Faraone, E P DuPre

  • 1Pediatric Psychopharmacology Unit, Child Psychiatry Service, Massachusetts General Hospital, Boston, 02114, USA.

The American Journal of Psychiatry
|October 2, 2001
PubMed
Summary

In girls, attention deficit hyperactivity disorder (ADHD) and learning disabilities share common familial risk factors. This suggests a genetic link, impacting families with ADHD and comorbid learning challenges.

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Area of Science:

  • Neurodevelopmental disorders
  • Genetics
  • Child psychology

Background:

  • Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder.
  • Learning disabilities affect academic achievement in children.
  • The relationship between ADHD and learning disabilities, particularly in girls, requires further investigation.

Purpose of the Study:

  • To investigate the familial risk of attention deficit hyperactivity disorder (ADHD) and learning disabilities in girls.
  • To determine if ADHD and learning disabilities share common genetic or familial risk factors in female subjects.

Main Methods:

  • Familial risk analysis was employed.
  • 679 first-degree relatives of three groups of index girls were assessed for ADHD and learning disabilities.
  • Groups included girls with ADHD and comorbid learning disability, girls with ADHD only, and a control group.

Main Results:

  • ADHD risk was elevated in families of girls with ADHD, regardless of learning disability status.
  • Learning disability risk was elevated only in families of girls with both ADHD and a learning disability.
  • Evidence suggested potential cosegregation of ADHD and learning disabilities within families, though not statistically significant.

Conclusions:

  • The findings support shared familial risk factors for ADHD and learning disabilities in girls.
  • This suggests a potential genetic overlap between these conditions in the female population.
  • Results extend previous research on the comorbidity of ADHD and learning disabilities to female subjects.