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Updated: Aug 12, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
[Multiple myeloma--advances in disease biology and implications for therapy]
1Department of Internal Medicine, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Niigata 951-8566, Japan.
Abstract:
Multiple myeloma (MM) is a systemic malignancy of pathologic plasma cells that is treatable with various chemotherapeutic agents and irradiation, but rarely curable. The mean age of affected patients is the mid-60s. Since the clinical presentation of multiple myeloma varies from asymptomatic to aggressive progression, there are many therapeutic options, such as follow-up without any treatment, and high-dose chemotherapy with stem cell transplantation. Recent advances in disease biology and implications for therapy are reviewed and summarized.
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