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[Organophosphate poisoning in inexperienced workers]
A Weissmann1, E Elran, S Givoni
1Obstetrics and Gynecology Department, Sheba Medical Center.
Harefuah
|October 3, 2001
Summary
Accidental organophosphate exposure in inexperienced agricultural workers caused severe poisoning symptoms. Prompt hospital treatment with atropine and toxogonin led to recovery, highlighting the need for safety protocols and emergency preparedness.
Area of Science:
- Toxicology
- Occupational Health
Background:
- Organophosphates are widely used as agricultural insecticides.
- Accidental exposure poses risks via dermal contact or inhalation.
Observation:
- Eight young, inexperienced male agricultural workers experienced unprotected dermal exposure to organophosphates.
- Symptoms included gastrointestinal distress, diaphoresis, hypersalivation, blurred vision, miosis, weakness, fasciculations, disorientation, and sleepiness.
- Low plasma acetylcholinesterase levels confirmed organophosphate intoxication.
Findings:
- All patients received prompt hospital admission and treatment with atropine and toxogonin.
- Patients were decontaminated and discharged within 48 hours in good condition.
- Rapid diagnosis and coordinated emergency response were crucial for successful management.
Implications:
- Highlights the critical need for experienced supervision for workers handling pesticides.
- Underscores the importance of hospital emergency drills for managing mass intoxication events.
- Emphasizes the effectiveness of timely medical intervention in organophosphate poisoning cases.