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[Tumor necrosis factor alpha and interleukin 1-beta in serum of patients with tick-borne encephalitis]

M Kondrusik1, S Pancewicz, J Zajkowska

  • 1Klinika Chorób Zakaznych i Neuroinfekcji AM w Białymstoku.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|October 3, 2001
PubMed

The purpose of this work was to evaluate the changes of IL-1 beta and TNF-alpha serum concentrations among patients with TBE (tick-borne encephalitis) of mild and severe clinical course. The detection of cytokines was performed by immunometric assay twice before and after treatment. There was no significant changes in IL-1 beta serum concentration after treatment in both groups of patients. But concentration of TNF-alpha decreased significantly after treatment in both groups of patients. It seems that changes of TNF-alpha concentration might be helpful in evaluation of efficacy of aseptic central nervous system treatment.

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