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Haemophilus influenza type b vaccine in Israel: experience in a paediatric ambulatory clinic

T Tauber1, E Lahat, G Dolinsky

  • 1Paediatric Ambulatory Clinic, Assaf Harofeh Medical Centre, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel.

Annals of Tropical Paediatrics
|October 3, 2001
PubMed

Insights

This study tracked 1,497 children vaccinated with Haemophilus influenza type b (Hib) vaccine. No Hib infections were confirmed, supporting the vaccine's continued use.

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • Vaccination policies in Israel are typically government-led.
  • This study initiated independent Haemophilus influenza type b (Hib) vaccination outside government control.
  • The study focused on a specific cohort receiving Hib vaccination at an ambulatory clinic.

Purpose of the Study:

  • To longitudinally monitor children vaccinated with the Hib vaccine.
  • To assess the incidence of Hib infection and hospitalizations in a vaccinated pediatric cohort.
  • To evaluate the effectiveness of independent Hib vaccination initiatives.

Main Methods:

  • A cohort of 1,497 children aged 2-52 months received the Hib vaccine.
  • Follow-up occurred over 7 years (1992-1999) via phone calls.
  • Parents reported hospitalizations and serious infectious diseases; cultures were analyzed.

Main Results:

  • 1,444 children were followed for the study period.
  • 36 hospitalizations occurred, with all blood and cerebrospinal fluid cultures negative.
  • No confirmed cases of Haemophilus influenza type b infection were identified in the vaccinated group.

Conclusions:

  • The study supports the continued use of the Haemophilus influenza type b vaccine.
  • Maintaining surveillance for Hib infection is recommended.
  • Independent vaccination programs can be effective in reducing disease incidence.

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