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IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms
A J Macpherson1, L Hunziker, K McCoy
1Institute of Experimental Immunology, Universitätsspital, Schmelzbergstrasse 12, CH8091, Zürich, Switzerland. amacpher@pathol.unizh.ch
Microbes and Infection
|October 3, 2001
Abstract:
IgA is the most abundant immunoglobulin produced in mammals; most is secreted as a dimer across mucous membranes. This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms.