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Implementing practice guidelines for appropriate antimicrobial usage: a systematic review.

P A Gross1, D Pujat

  • 1Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA. pgross237@aol.com

Medical Care
|October 5, 2001
PubMed
Summary
This summary is machine-generated.

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Multifaceted strategies effectively promote appropriate antimicrobial use, combating rising resistance. These methods include academic detailing, feedback, and interactive sessions for healthcare professionals.

Area of Science:

  • Infectious Diseases
  • Health Services Research
  • Pharmacology

Background:

  • Antimicrobial resistance is a growing global health threat.
  • Inappropriate antimicrobial use is a significant contributing factor to resistance.
  • Guidelines exist to promote appropriate antimicrobial prescribing.

Purpose of the Study:

  • To systematically review studies on implementing antimicrobial use guidelines.
  • To identify effective implementation strategies for appropriate antimicrobial use.
  • To assess the impact of these strategies on antimicrobial prescribing outcomes.

Main Methods:

  • Systematic review of comparative studies from the Medline database.
  • Included studies focused on guideline implementation for appropriate antimicrobial use in common infections (community- and hospital-acquired).

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  • Analysis incorporated treatment effects and cost estimates.

    • Main Results:

    • Forty studies demonstrated the effectiveness of various implementation methods.
    • Multifaceted implementation strategies were most successful in promoting appropriate antimicrobial use.
    • Effective individual methods included academic detailing, multidisciplinary feedback, guideline adaptation, interactive sessions, and computer-assisted care.

    Conclusions:

    • Multifaceted approaches are key to improving appropriate antimicrobial prescribing.
    • Specific interventions like academic detailing and feedback are valuable components of implementation strategies.
    • Effective implementation of guidelines can help mitigate antimicrobial resistance.