Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simultaneous assessment of occupational exposures from multiple worker groups.

M A Weaver1, L L Kupper, D Taylor

  • 1Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill, NC 27599-7400, USA.

The Annals of Occupational Hygiene
|October 5, 2001
PubMed
Summary

This study extends methods for assessing workplace exposures to analyze multiple worker groups simultaneously. The new approach efficiently identifies overexposed groups, aiding in targeted intervention strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Congenital cataract and multisystem disorders.

Eye (London, England)·2000
Same author

Effectiveness of professional--peer group treatment: symptom management for women with PMS.

Research in nursing & health·2000
Same author

Visualization of head-head interactions in the inhibited state of smooth muscle myosin.

The Journal of cell biology·1999
Same author

Long-term interferon-alpha 2A does not induce sustained hematologic remission in younger patients with essential thrombocythemia.

Leukemia & lymphoma·1999
Same author

Iatrogenic drug dependence--a problem in intensive care? Case study and literature review.

Intensive & critical care nursing·1999
Same author

Application of mixed models to assess exposures monitored by construction workers during hot processes.

The Annals of occupational hygiene·1999

Area of Science:

  • Occupational hygiene and environmental statistics
  • Exposure assessment and risk management
  • Statistical modeling for public health

Background:

  • Existing methods assess workplace exposures on a group-by-group basis.
  • Simultaneous assessment of multiple worker groups within an industry is needed.
  • Log-normal distribution and mixed-effects regression models are commonly used for exposure data.

Purpose of the Study:

  • To extend existing methods for simultaneous assessment of data from multiple worker groups.
  • To develop a procedure for testing worker overexposure, conditional on variance component homogeneity.
  • To provide recommendations for study design and intervention strategies.

Main Methods:

  • Extended Rappaport et al. and Lyles et al. methods for simultaneous multi-group analysis.

Related Experiment Videos

  • Utilized mixed-effects regression models assuming log-normally distributed exposures.
  • Employed a likelihood ratio test to assess homogeneity of within-worker variance components and a conditional procedure for overexposure testing.

    • Main Results:

    • The extended methods successfully fit models to data from multiple groups, even with limited data per group.
    • The overexposure testing procedure yielded consistent conclusions under both homogeneous and heterogeneous within-worker variance assumptions.
    • Simulation studies indicated that the testing procedure maintains adequate significance levels when using a preliminary likelihood ratio test with a significance level of at least 0.01.

    Conclusions:

    • The developed methods enable robust simultaneous assessment of workplace exposures across multiple groups.
    • The procedure effectively identifies overexposed worker groups, supporting targeted risk management.
    • Recommendations are provided for study design and determining the most beneficial intervention types (e.g., engineering controls vs. individual-level interventions).