Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adjunctive pharmacotherapy for coronary stenting.

S A Harding1, D L Walters, I F Palacios

  • 1Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

Current Opinion in Cardiology
|October 5, 2001
PubMed
Summary

Coronary stenting significantly reduces early ischemic events with anticoagulation and antiplatelet therapy. Novel drug-coated stents show promise for preventing late restenosis, with ongoing trials awaited.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Loss of flavonol 3-O-glucosyltransferase activity confers soybean resistance to leaf-chewing insects.

The Plant journal : for cell and molecular biology·2026
Same author

Clinical characteristics and outcomes of Australian and Indian ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI).

Indian heart journal·2024
Same author

Re: The potential of abbreviated breast MRI (FAST MRI) as a tool for breast cancer screening: a systematic review and meta-analysis. A reply.

Clinical radiology·2021
Same author

The potential utility of abbreviated breast MRI (FAST MRI) as a tool for breast cancer screening: a systematic review and meta-analysis.

Clinical radiology·2020
Same author

The trajectory of positive psychological change in a head and neck cancer population.

International journal of oral and maxillofacial surgery·2017
Same author

Bipolar radiofrequency renal denervation with the Vessix catheter in patients with resistant hypertension: 2-year results from the REDUCE-HTN trial.

Journal of human hypertension·2017

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Percutaneous coronary intervention (PCI) outcomes are improved by coronary stents, leading to increased usage.
  • Coronary stenting presents challenges, including early ischemic events and late restenosis.
  • Current therapies combine unfractionated heparin (UFH) with antiplatelet agents to mitigate early risks.

Purpose of the Study:

  • To review current strategies for managing complications associated with coronary stenting.
  • To evaluate the potential of novel anticoagulants and drug-coated stents in improving PCI outcomes.

Main Methods:

  • Review of existing literature on anticoagulation and antiplatelet therapies post-stenting.
  • Analysis of preliminary data and ongoing trials for drug-eluting stents and alternative anticoagulants.

Related Experiment Videos

Main Results:

  • Combination therapy significantly reduces early ischemic events after stenting.
  • Systemic pharmacotherapy has largely failed to reduce in-stent restenosis.
  • Drug-coated stents demonstrate promising preliminary results in inhibiting neointimal proliferation.

Conclusions:

  • Current anticoagulation and antiplatelet regimens effectively manage early stent-related complications.
  • Drug-coated stents represent a promising future strategy for preventing late in-stent restenosis.
  • Further investigation into low molecular weight heparin (LMWH) and direct thrombin inhibitors is warranted.