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Differentiation of calcification from chronic hemorrhage with corrected gradient echo phase imaging
1Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. rgupta@sgpgi.ac.in
Journal of Computer Assisted Tomography
|October 5, 2001
Summary
Corrected gradient echo phase imaging effectively differentiates calcified granuloma from chronic hemorrhage. This technique shows distinct phase shifts, potentially reducing the need for CT scans.
Area of Science:
- Radiology
- Medical Imaging
Background:
- Differentiating calcified granuloma from chronic hemorrhage is crucial for accurate diagnosis.
- Gradient echo phase imaging is a novel technique for tissue characterization.
Purpose of the Study:
- To prospectively assess the utility of corrected gradient echo phase imaging in distinguishing calcified granuloma from chronic hemorrhage.
- To evaluate the diagnostic accuracy of this imaging technique.
Main Methods:
- Eighty-five patients with calcifications and hemorrhages underwent corrected gradient echo phase imaging.
- Computed tomography (CT) served as the gold standard for calcification confirmation.
Main Results:
- All calcified lesions exhibited positive phase shifts, while chronic hemorrhages showed negative phase shifts.
- Specific phase shift patterns were observed at different echo times (TE).
- The technique demonstrated reliable differentiation across various anatomical locations, including the basal ganglia.
Conclusions:
- Corrected gradient echo phase imaging accurately differentiates calcified granuloma from chronic hemorrhage.
- This imaging modality may serve as a non-invasive alternative to CT for confirmation.