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Updated: Aug 10, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
Published on: November 23, 2019
Performance evaluation of an automated system for registration and postprocessing of CT scans
N M Alpert1, D Berdichevsky, Z Levin
1Department of Radiology, Massachusetts General Hospital, Boston, MA, USA. alpert@pet.mgh.harvard.edu
Abstract:
A prototype system optimized for automatic registration of CT scans and applications such as subtraction enhancement and CT angiography was evaluated. Co-registration was performed on 50 studies of various types, including CT angiograms. Mean registration speed was 109 s; accuracy was 2.0 mm. Examples of subtraction enhancement and automatic extraction of the vascular tree are provided. Unattended registration was demonstrated in routine application. Subtraction-enhanced images and extraction of the vascular tree may be useful in clinical practice.
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