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Postpartum herpes simplex endometritis. A case report.

M J Hixson, J H Collins

    The Journal of Reproductive Medicine
    |October 5, 2001
    PubMed
    Summary
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    Postpartum herpes simplex virus (HSV) endometritis can cause persistent fever unresponsive to antibiotics. Prompt treatment with intravenous acyclovir effectively resolves symptoms, aiding diagnosis.

    Area of Science:

    • Obstetrics and Gynecology
    • Infectious Diseases
    • Virology

    Background:

    • Postpartum endometritis is a known complication of herpes simplex virus (HSV) infection.
    • Clinical diagnosis and intravenous acyclovir treatment for HSV endometritis have been previously documented.

    Observation:

    • A patient presented with persistent postpartum fever following cesarean delivery.
    • The fever mimicked septic pelvic thrombophlebitis and was unresponsive to broad-spectrum antimicrobials and heparin.
    • Active herpetic lesions and a positive cervical HSV culture confirmed the diagnosis.

    Findings:

    • Intravenous acyclovir administration led to rapid resolution of the patient's fever.
    • The clinical presentation and response to treatment were consistent with herpes simplex endometritis.

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    Implications:

    • Consider herpes simplex endometritis in postpartum fever cases unresponsive to standard therapies.
    • Early recognition and acyclovir treatment are crucial for managing this condition.