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Eradicating chancroid.

R Steen1

  • 1Family Health International, 2101 Wilson Boulevard, Suite 700, Arlington, VA 22201, USA. rsteen@together.net

Bulletin of the World Health Organization
|October 5, 2001
PubMed
Summary

Chancroid, caused by Haemophilus ducreyi, is a common genital ulcer disease that fuels HIV transmission. Effective treatments and prevention strategies, including hygiene and male circumcision, make chancroid eradication a feasible public health goal.

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Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Genital ulcers, particularly chancroid caused by Haemophilus ducreyi, are significant cofactors in HIV transmission, especially in high HIV prevalence regions.
  • Chancroid is endemic in areas with high HIV prevalence, linked to sexual networks with frequent partner changes and commercial sex activity.

Purpose of the Study:

  • To analyze the epidemiology of chancroid and its relationship with HIV transmission.
  • To evaluate the feasibility of chancroid eradication as a public health objective.

Main Methods:

  • Review of epidemiological data on chancroid prevalence and its correlation with HIV epidemics.
  • Analysis of the impact of interventions such as hygiene, male circumcision, and antibiotic treatment on chancroid transmission.
  • Historical analysis of chancroid's decline in Europe and North America.

Main Results:

  • Haemophilus ducreyi thrives in specific socio-sexual environments, and its elimination from vulnerable groups leads to community-wide disappearance.
  • Chancroid prevalence has declined in several countries, potentially contributing to HIV epidemic stabilization.
  • Social changes, rather than solely antibiotics, historically reduced chancroid endemicity.

Conclusions:

  • Chancroid eradication is an achievable public health goal.
  • Strategies focusing on protecting sex workers and clients, alongside improved STD curative services, are effective.
  • Reducing chancroid burden can contribute to stabilizing HIV epidemics.

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