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Updated: Jul 24, 2026

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
Published on: August 24, 2019
Clostridial mycotic aneurysm of the thoracoabdominal aorta--a case report
R C Morrison1, P J DiMuzio, M Kahn
1Division of Cardiothoracic Surgery, Department of Surgery, Jefferson Medical College, 111 South 11th Street, Philadelphia, PA 19107, USA.
Abstract:
Clostridial infection of the aorta is a rare and life-threatening condition. The management of a mycotic aneurysm involving the thoracoabdominal aorta due to Clostridium septicum infection is presented. Successful surgical management of the aortic infection involved arterial resection, wide debridement of the surrounding tissues, and in situ graft replacement. Sixteen additional cases of clostridial infection of the aortoiliac segment reported in the literature are also summarized. In ten of these 17 cases, an associated colonic adenocarcinoma was documented.
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