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[New indications of ivermectin].
1Département des maladies infectieuses, tropicales et de parasitologie-mycologie, hôpital de la Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris, France.
La Revue De Medecine Interne
|October 6, 2001
Summary
Ivermectin, a broad-spectrum antiparasitic drug, is effective against nematodes and ectoparasites. It is a recommended treatment for onchocerciasis, lymphatic filariasis, strongyloidiasis, and scabies.
Area of Science:
- Pharmacology
- Antiparasitic Agents
Context:
- Ivermectin is a semi-synthetic macrocyclic lactone derivative.
- It exhibits broad-spectrum activity against nematodes and ectoparasites.
Purpose:
- To review the established and emerging therapeutic applications of ivermectin.
- To highlight its efficacy in treating parasitic infections.
Summary:
- Ivermectin is a key treatment for onchocerciasis and lymphatic filariasis.
- Recent recommendations include its use for strongyloidiasis and scabies.
- Promising results are also noted for ascariasis, cutaneous larva migrans, loiasis, and head lice.
Impact:
- Expands the therapeutic armamentarium for neglected tropical diseases.
- Offers effective treatment options for common parasitic infestations.
- Supports the repurposing of existing drugs for new indications.