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Published on: July 19, 2018
Nutritional markers during peritoneal dialysis: data from the 1998 Peritoneal Dialysis Core Indicators Study
M J Flanigan1, D L Frankenfield, B F Prowant
1University of Iowa College of Medicine, Iowa City, USA. mjf@inav.net
Summary
Adult U.S. peritoneal dialysis patients often have low serum albumin, despite normal weight and BMI. Nutritional status indicators like serum albumin and body mass index (BMI) provide conflicting results in these patients.
Area of Science:
- Nephrology
- Nutritional Science
- Public Health
Background:
- Peritoneal dialysis (PD) is a common treatment for end-stage renal disease (ESRD).
- Assessing nutritional status in PD patients is crucial for managing their health outcomes.
- Existing nutritional indicators may yield disparate results in PD populations.
Purpose of the Study:
- To explore the nutritional status of adult U.S. peritoneal dialysis (PD) patients.
- To compare various nutritional indices and their correlation with patient characteristics and dialysis parameters.
Main Methods:
- Prospective, cross-sectional prevalence survey of a national random sample of 1381 adult U.S. PD patients.
- Data collected on patient demographics, ESRD causes, dialysis adequacy (Kt/V urea, creatinine clearance), and nutritional markers (serum albumin, BMI, nPNA, %LBM).
Main Results:
- The mean serum albumin was 3.5 g/dL, with 43% below recommended levels.
- Serum albumin correlated negatively with age, diabetes, female gender, and dialysis parameters.
- Nutritional indicators like BMI, lean body mass, and serum albumin provided varying prevalence estimates of nutritional stress (10-50%).
Conclusions:
- PD patients frequently exhibit marginal serum albumin levels, which may not align with other nutritional markers.
- High peritoneal permeability and dialysis adequacy influence serum albumin levels.
- Discrepancies among nutritional indicators highlight the complexity of assessing nutritional status in PD patients.
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